5DO4

Thrombin-RNA aptamer complex

Summary for 5DO4

• Entry DOI: 10.2210/pdb5do4/pdb
• Related PRD ID: PRD_000020
• Descriptor: Thrombin light chain, MAGNESIUM ION, Thrombin heavy chain, ... (11 entities in total)
• Functional Keywords: thrombin-rna aptamer, phosphorodithioate rna, ps2-rna, ps2 linkage, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 43284.77

Authors

Pallan, P.S.,Egli, M. (deposition date: 2015-09-10, release date: 2016-09-14, Last modification date: 2023-09-27)

• Primary citation: Abeydeera, N.D.,Egli, M.,Cox, N.,Mercier, K.,Conde, J.N.,Pallan, P.S.,Mizurini, D.M.,Sierant, M.,Hibti, F.E.,Hassell, T.,Wang, T.,Liu, F.W.,Liu, H.M.,Martinez, C.,Sood, A.K.,Lybrand, T.P.,Frydman, C.,Monteiro, R.Q.,Gomer, R.H.,Nawrot, B.,Yang, X.; Evoking picomolar binding in RNA by a single phosphorodithioate linkage.; Nucleic Acids Res., 44:8052-8064, 2016; PubMed: 27566147; DOI: 10.1093/nar/gkw725

Experimental method

X-RAY DIFFRACTION (1.859 Å)