5DN2
Human NRP2 b1 domain in complex with the peptide corresponding to the C-terminus of VEGF-A
Summary for 5DN2
Entry DOI | 10.2210/pdb5dn2/pdb |
Descriptor | Neuropilin-2, Vascular endothelial growth factor A, 1,4-DIETHYLENE DIOXIDE, ... (5 entities in total) |
Functional Keywords | signaling protein, neuropilin-2, vegfa, angiogenesis, heparin, receptor |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane ; Single-pass type I membrane protein . Isoform s9: Secreted : O60462 Secreted : P15692 |
Total number of polymer chains | 7 |
Total formula weight | 81763.29 |
Authors | Tsai, Y.C.I.,Frankel, P.,Fotinou, C.,Rana, R.,Zachary, I.,Djordjevic, S. (deposition date: 2015-09-09, release date: 2016-07-20, Last modification date: 2024-01-10) |
Primary citation | Tsai, Y.C.,Fotinou, C.,Rana, R.,Yelland, T.,Frankel, P.,Zachary, I.,Djordjevic, S. Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket. Febs J., 283:1921-1934, 2016 Cited by PubMed: 26991001DOI: 10.1111/febs.13711 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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