5DLT
Crystal structure of Autotaxin (ENPP2) with 7-alpha-hydroxycholesterol
Summary for 5DLT
Entry DOI | 10.2210/pdb5dlt/pdb |
Descriptor | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (10 entities in total) |
Functional Keywords | autotaxin, enpp2, lpa, steroids, bile salts, hydrolase |
Biological source | Rattus norvegicus (norway Rat) |
Total number of polymer chains | 1 |
Total formula weight | 98876.31 |
Authors | Hausmann, J.,Joosten, R.P.,Perrakis, A. (deposition date: 2015-09-07, release date: 2016-04-13, Last modification date: 2024-01-10) |
Primary citation | Keune, W.J.,Hausmann, J.,Bolier, R.,Tolenaars, D.,Kremer, A.,Heidebrecht, T.,Joosten, R.P.,Sunkara, M.,Morris, A.J.,Matas-Rico, E.,Moolenaar, W.H.,Oude Elferink, R.P.,Perrakis, A. Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. Nat Commun, 7:11248-11248, 2016 Cited by PubMed: 27075612DOI: 10.1038/ncomms11248 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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