5DLT

Crystal structure of Autotaxin (ENPP2) with 7-alpha-hydroxycholesterol

5DLT の概要

• エントリーDOI: 10.2210/pdb5dlt/pdb
• 分子名称: Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (10 entities in total)
• 機能のキーワード: autotaxin, enpp2, lpa, steroids, bile salts, hydrolase
• 由来する生物種: Rattus norvegicus (norway Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 98876.31

構造登録者

Hausmann, J.,Joosten, R.P.,Perrakis, A. (登録日: 2015-09-07, 公開日: 2016-04-13, 最終更新日: 2024-01-10)

• 主引用文献: Keune, W.J.,Hausmann, J.,Bolier, R.,Tolenaars, D.,Kremer, A.,Heidebrecht, T.,Joosten, R.P.,Sunkara, M.,Morris, A.J.,Matas-Rico, E.,Moolenaar, W.H.,Oude Elferink, R.P.,Perrakis, A.; Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling.; Nat Commun, 7:11248-11248, 2016; PubMed: 27075612; DOI: 10.1038/ncomms11248

実験手法

X-RAY DIFFRACTION (1.6 Å)