5D4D

Crystal structure of Thermus thermophilus product complex for transcription initiation with NAD and CTP

5D4D の概要

• エントリーDOI: 10.2210/pdb5d4d/pdb
• 関連するPDBエントリー: 4G7H 5D4C 5D4E
• 分子名称: DNA-directed RNA polymerase subunit alpha, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... (15 entities in total)
• 機能のキーワード: rna polymerase, transcription initiation, bacterial, ncin, non-canonical initiating nucleotide, primer-dependent initiation, dna, single-stranded, dna-directed rna polymerases, gene expression regulation, promoter regions, genetic, protein conformation, sigma factor, transcription-dna complex, transcription/dna
• 由来する生物種: Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039); 詳細
• 細胞内の位置: Cytoplasm : Q72L95
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 889360.42

構造登録者

Zhang, Y.,Ebright, R.H. (登録日: 2015-08-07, 公開日: 2016-07-06, 最終更新日: 2024-05-29)

• 主引用文献: Bird, J.G.,Zhang, Y.,Tian, Y.,Panova, N.,Barvik, I.,Greene, L.,Liu, M.,Buckley, B.,Krasny, L.,Lee, J.K.,Kaplan, C.D.,Ebright, R.H.,Nickels, B.E.; The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.; Nature, 535:444-447, 2016; PubMed: 27383794; DOI: 10.1038/nature18622

実験手法

X-RAY DIFFRACTION (3 Å)