5D3Z
Crystal structure of the thioesterase domain of deoxyerythronolide B synthase in complex with a small phosphonate inhibitor
5D3Z の概要
エントリーDOI | 10.2210/pdb5d3z/pdb |
分子名称 | Erythronolide synthase, modules 5 and 6, prop-2-en-1-ylphosphonic acid, PENTAETHYLENE GLYCOL, ... (5 entities in total) |
機能のキーワード | thioesterase domaine alpha / beta hydrolase fold deoxyerythronolide b synthase allyl phosphonate inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
由来する生物種 | Saccharopolyspora erythraea |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 29181.56 |
構造登録者 | Bergeret, F.,Argyropoulos, P.,Boddy, C.N.,Schmeing, T.M. (登録日: 2015-08-06, 公開日: 2015-12-09, 最終更新日: 2023-09-27) |
主引用文献 | Argyropoulos, P.,Bergeret, F.,Pardin, C.,Reimer, J.M.,Pinto, A.,Boddy, C.N.,Schmeing, T.M. Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. Biochim.Biophys.Acta, 1860:486-497, 2015 Cited by PubMed: 26592346DOI: 10.1016/j.bbagen.2015.11.007 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.1 Å) |
構造検証レポート
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