5D3K

Crystal structure of the thioesterase domain of deoxyerythronolide B synthase

Summary for 5D3K

• Entry DOI: 10.2210/pdb5d3k/pdb
• Related: 5D2R
• Descriptor: Erythronolide synthase, modules 5 and 6, PENTAETHYLENE GLYCOL, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: thioesterase domaine alpha / beta hydrolase fold deoxyerythronolide b synthase, hydrolase
• Biological source: Saccharopolyspora erythraea
• Total number of polymer chains: 1
• Total formula weight: 29377.94

Authors

Bergeret, F.,Argyropoulos, P.,Boddy, C.N.,Schmeing, T.M. (deposition date: 2015-08-06, release date: 2015-12-09, Last modification date: 2023-09-27)

• Primary citation: Argyropoulos, P.,Bergeret, F.,Pardin, C.,Reimer, J.M.,Pinto, A.,Boddy, C.N.,Schmeing, T.M.; Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis.; Biochim.Biophys.Acta, 1860:486-497, 2015; PubMed: 26592346; DOI: 10.1016/j.bbagen.2015.11.007

Experimental method

X-RAY DIFFRACTION (1.7 Å)