5CUQ

Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase

5CUQ の概要

• エントリーDOI: 10.2210/pdb5cuq/pdb
• 分子名称: Nonstructural protein NS5, N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA (3 entities in total)
• 機能のキーワード: inhibitor, complex, dengue virus, methyltransferase, viral protein-inhibitor complex, viral protein/inhibitor
• 由来する生物種: Dengue virus 3
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60884.02

構造登録者

Brecher, B.,Chen, H.,Li, Z.,Banavali, N.K.,Jones, S.A.,Zhang, J.,Kramer, L.D.,Li, H.M. (登録日: 2015-07-24, 公開日: 2016-02-03, 最終更新日: 2023-09-27)

• 主引用文献: Brecher, M.,Chen, H.,Li, Z.,Banavali, N.K.,Jones, S.A.,Zhang, J.,Kramer, L.D.,Li, H.; Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase.; Acs Infect Dis., 1:340-349, 2015; PubMed: 26726314; DOI: 10.1021/acsinfecdis.5b00070

実験手法

X-RAY DIFFRACTION (1.696 Å)