5CP3

Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides in Complex with Sulfathiazole

Summary for 5CP3

• Entry DOI: 10.2210/pdb5cp3/pdb
• Related: 5CP7
• Descriptor: Light Chain of Antigen-Binding Fragment of Monoclonal Antibody of 4C7, Heavy Chain of Antigen-Binding Fragment of Monoclonal Antibody of 4C7, 4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, ... (6 entities in total)
• Functional Keywords: sulfathiazole, anti-sulfonamides antibody, antigen-binding fragment, complex, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 47356.70

Authors

Wang, Z.,Shen, J.,Li, C.,Li, Y.,Wen, K.,Yu, X.,Zhang, X. (deposition date: 2015-07-21, release date: 2015-08-05, Last modification date: 2023-11-08)

• Primary citation: Li, C.,Liang, X.,Wen, K.,Li, Y.,Zhang, X.,Ma, M.,Yu, X.,Yu, W.,Shen, J.,Wang, Z.; Class-specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity.; Anal. Chem., 91:2392-2400, 2019; PubMed: 30580515; DOI: 10.1021/acs.analchem.8b05174

Experimental method

X-RAY DIFFRACTION (1.99 Å)