5CO3

Crystal structure of a novel disulfide oxidoreductase from Deinococcus radiodurans crystallized in presence of DTT

5CO3 の概要

• エントリーDOI: 10.2210/pdb5co3/pdb
• 関連するPDBエントリー: 5cnw 5cp1
• 分子名称: FrnE protein, GLYCEROL (3 entities in total)
• 機能のキーワード: disulfide oxidoreductase, disulfide isomerase, frne, oxidoreductase
• 由来する生物種: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28585.97

構造登録者

Bihani, S.C.,Panicker, L.,Kumar, V. (登録日: 2015-07-19, 公開日: 2016-07-20, 最終更新日: 2024-11-20)

主引用文献

Bihani, S.C.,Panicker, L.,Rajpurohit, Y.S.,Misra, H.S.,Kumar, V.
drFrnE Represents a Hitherto Unknown Class of Eubacterial Cytoplasmic Disulfide Oxido-Reductases.
Antioxid. Redox Signal., 28:296-310, 2018

PubMed Abstract: Living cells employ thioredoxin and glutaredoxin disulfide oxido-reductases to protect thiol groups in intracellular proteins. FrnE protein of Deinococcus radiodurans (drFrnE) is a disulfide oxido-reductase that is induced in response to Cd exposure and is involved in cadmium and radiation tolerance. The aim of this study is to probe structure, function, and cellular localization of FrnE class of proteins.

PubMed: 28899103
DOI: 10.1089/ars.2016.6960

実験手法

X-RAY DIFFRACTION (1.65 Å)