5CNN

Crystal structure of the EGFR kinase domain mutant I682Q

Summary for 5CNN

• Entry DOI: 10.2210/pdb5cnn/pdb
• Related: 5CNO
• Descriptor: Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: kinase egfr, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 80330.35

Authors

Kovacs, E.,Das, R.,Mirza, A.,Jura, N.,Barros, T.,Kuriyan, J. (deposition date: 2015-07-17, release date: 2015-07-29, Last modification date: 2023-09-27)

• Primary citation: Kovacs, E.,Das, R.,Wang, Q.,Collier, T.S.,Cantor, A.,Huang, Y.,Wong, K.,Mirza, A.,Barros, T.,Grob, P.,Jura, N.,Bose, R.,Kuriyan, J.; Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor.; Mol.Cell.Biol., 35:3083-3102, 2015; PubMed: 26124280; DOI: 10.1128/MCB.00248-15

Experimental method

X-RAY DIFFRACTION (1.9 Å)