5CJX

Crystal structure of 8ANC195 Fab in complex with BG505 SOSIP.664 HIV-1 Env trimer

5CJX の概要

• エントリーDOI: 10.2210/pdb5cjx/pdb
• 分子名称: 8ANC195 G52K5 heavy chain, IG gamma-1 chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: hiv-1 env trimer, ig fold, antibody, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 377123.55

構造登録者

Scharf, L.,Bjorkman, P.J. (登録日: 2015-07-15, 公開日: 2015-09-23, 最終更新日: 2023-09-27)

• 主引用文献: Scharf, L.,Wang, H.,Gao, H.,Chen, S.,McDowall, A.W.,Bjorkman, P.J.; Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.; Cell, 162:1379-1390, 2015; PubMed: 26359989; DOI: 10.1016/j.cell.2015.08.035

実験手法

X-RAY DIFFRACTION (3.584 Å)