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5CGV

2009 H1N1 PA endonuclease in complex with L-742,001

Summary for 5CGV
Entry DOI10.2210/pdb5cgv/pdb
DescriptorPolymerase acidic protein, MANGANESE (II) ION, (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, ... (5 entities in total)
Functional Keywordsinfluenza resistance endonuclease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceInfluenza A virus
Total number of polymer chains1
Total formula weight22586.02
Authors
Kumar, G.,White, S.W. (deposition date: 2015-07-09, release date: 2016-03-23, Last modification date: 2023-09-27)
Primary citationSong, M.S.,Kumar, G.,Shadrick, W.R.,Zhou, W.,Jeevan, T.,Li, Z.,Slavish, P.J.,Fabrizio, T.P.,Yoon, S.W.,Webb, T.R.,Webby, R.J.,White, S.W.
Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 113:3669-3674, 2016
Cited by
PubMed: 26976575
DOI: 10.1073/pnas.1519772113
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.17 Å)
Structure validation

217705

数据于2024-03-27公开中

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