5CGN

Structure of quasiracemic Ala-Magainin 2 with a beta amino acid substitution at position 8

Summary for 5CGN

• Entry DOI: 10.2210/pdb5cgn/pdb
• Related: 5CGO
• Descriptor: D-Ala-Magainin Derivative, L-ACPC8-Ala-Magainin, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: antimicrobial, quasiracemate, homochiral dimerization, beta amino acid, antimicrobial protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 8
• Total formula weight: 20143.07

Authors

Hayouka, Z.,Thomas, N.C.,Mortenson, D.E.,Satyshur, K.A.,Weisblum, B.,Forest, K.T.,Gellman, S.H. (deposition date: 2015-07-09, release date: 2015-09-23, Last modification date: 2023-11-15)

• Primary citation: Hayouka, Z.,Thomas, N.C.,Mortenson, D.E.,Satyshur, K.A.,Weisblum, B.,Forest, K.T.,Gellman, S.H.; Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.; J.Am.Chem.Soc., 137:11884-11887, 2015; PubMed: 26369301; DOI: 10.1021/jacs.5b07206

Experimental method

X-RAY DIFFRACTION (2.2 Å)