5CGI
Yeast 20S proteasome beta5-G48C mutant in complex with ONX 0914
Summary for 5CGI
Entry DOI | 10.2210/pdb5cgi/pdb |
Related | 1RYP |
Related PRD ID | PRD_000991 |
Descriptor | Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (20 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, proteasome, mutant, inhibitor, binding analysis, hydrolase/hydrolase inhibitor |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 28 |
Total formula weight | 735743.45 |
Authors | Dubiella, C.,Groll, M. (deposition date: 2015-07-09, release date: 2015-11-25, Last modification date: 2024-01-10) |
Primary citation | Dubiella, C.,Baur, R.,Cui, H.,Huber, E.M.,Groll, M. Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine. Angew.Chem.Int.Ed.Engl., 54:15888-15891, 2015 Cited by PubMed: 26563572DOI: 10.1002/anie.201506631 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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