5CCK
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC315 Fab
Summary for 5CCK
Entry DOI | 10.2210/pdb5cck/pdb |
Related | 5AWN |
EMDB information | 3067 |
Descriptor | Antibody 3BC315 Fab heavy chain, Antibody 3BC315 Fab light chain, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ... (4 entities in total) |
Functional Keywords | hiv-1, env, bnab, antibody, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 48230.16 |
Authors | Lee, J.H.,Ward, A.B.,Wilson, I.A. (deposition date: 2015-07-02, release date: 2015-10-07, Last modification date: 2019-12-11) |
Primary citation | Lee, J.H.,Leaman, D.P.,Kim, A.S.,Torrents de la Pena, A.,Sliepen, K.,Yasmeen, A.,Derking, R.,Ramos, A.,de Taeye, S.W.,Ozorowski, G.,Klein, F.,Burton, D.R.,Nussenzweig, M.C.,Poignard, P.,Moore, J.P.,Klasse, P.J.,Sanders, R.W.,Zwick, M.B.,Wilson, I.A.,Ward, A.B. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat Commun, 6:8167-8167, 2015 Cited by PubMed: 26404402DOI: 10.1038/ncomms9167 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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