5CC7

Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 1H-indole-6-carboxylic acid

Summary for 5CC7

• Entry DOI: 10.2210/pdb5cc7/pdb
• Descriptor: Malate synthase G, MAGNESIUM ION, 1H-indole-6-carboxylic acid, ... (4 entities in total)
• Functional Keywords: complex, fragment, transferase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Cellular location: Cytoplasm : P9WK17
• Total number of polymer chains: 1
• Total formula weight: 80642.20

Authors

Huang, H.-L.,Sacchettini, J.C. (deposition date: 2015-07-01, release date: 2016-08-10, Last modification date: 2023-09-27)

• Primary citation: Huang, H.-L.,Krieger, I.V.,Gawandi, V.B.,Parai, M.,Sacchettini, J.C.; Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.12 Å)