5CC3
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 6-bromo-1H-indole-2-carboxylic acid
Summary for 5CC3
Entry DOI | 10.2210/pdb5cc3/pdb |
Descriptor | Malate synthase G, MAGNESIUM ION, 6-bromanyl-1H-indole-2-carboxylic acid, ... (4 entities in total) |
Functional Keywords | complex, fragment, transferase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Cellular location | Cytoplasm : P9WK17 |
Total number of polymer chains | 1 |
Total formula weight | 80745.40 |
Authors | Huang, H.-L.,Sacchettini, J.C. (deposition date: 2015-07-01, release date: 2016-08-10, Last modification date: 2023-09-27) |
Primary citation | Huang, H.-L.,Krieger, I.V.,Gawandi, V.B.,Parai, M.,Sacchettini, J.C. Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.204 Å) |
Structure validation
Download full validation report