5BSC
Crystal structure of K66A mutant of human macrophage migration inhibitory factor
Summary for 5BSC
| Entry DOI | 10.2210/pdb5bsc/pdb |
| Related | 5BS9 5BSI 5BSJ |
| Descriptor | Macrophage migration inhibitory factor, ISOPROPYL ALCOHOL (3 entities in total) |
| Functional Keywords | isomerase, surface, mutation |
| Biological source | Homo sapiens (Human) |
| Cellular location | Secreted: P14174 |
| Total number of polymer chains | 3 |
| Total formula weight | 37071.15 |
| Authors | Pantouris, G.,Lolis, E. (deposition date: 2015-06-01, release date: 2015-09-30, Last modification date: 2023-09-27) |
| Primary citation | Pantouris, G.,Syed, M.A.,Fan, C.,Rajasekaran, D.,Cho, T.Y.,Rosenberg, E.M.,Bucala, R.,Bhandari, V.,Lolis, E.J. An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22:1197-1205, 2015 Cited by PubMed: 26364929DOI: 10.1016/j.chembiol.2015.08.006 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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