5BMV
CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-Vinblastine COMPLEX
Summary for 5BMV
Entry DOI | 10.2210/pdb5bmv/pdb |
Descriptor | Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, ... (13 entities in total) |
Functional Keywords | complex, structural protein |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasm, cytoskeleton: P81947 P02554 Golgi apparatus : P63043 |
Total number of polymer chains | 6 |
Total formula weight | 265948.62 |
Authors | |
Primary citation | Wang, Y.,Benz, F.W.,Wu, Y.,Wang, Q.,Chen, Y.,Chen, X.,Li, H.,Zhang, Y.,Zhang, R.,Yang, J. Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules. Mol.Pharmacol., 89:233-242, 2016 Cited by PubMed: 26660762DOI: 10.1124/mol.115.100149 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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