5B5J

Hen egg white lysozyme with boron tracedrug UTX-97

Summary for 5B5J

• Entry DOI: 10.2210/pdb5b5j/pdb
• Descriptor: Lysozyme C, 2-cyano-3-((6-(((2-((2-cyanoethyl)(borocaptate-10B)sulfonio)acetyl)carbamoyl)oxy)hexyl)amino)quinoxaline 1,4-dioxide, SODIUM ION, ... (4 entities in total)
• Functional Keywords: boron cluster drug, complex, hydrolase
• Biological source: Gallus gallus (Chicken)
• Cellular location: Secreted: P00698
• Total number of polymer chains: 1
• Total formula weight: 15591.72

Authors

Morimoto, Y. (deposition date: 2016-05-11, release date: 2017-06-28)

• Primary citation: Morimoto, Y.,Nagasawa, H.,Uto, Y.,Chatake, T.,Hori, H.; Structural Insight Into Protein Binding of Boron Tracedrug UTX-97 Revealed by the Co-Crystal Structure With Lysozyme at 1.26 angstrom Resolution.; J Pharm Sci, 105:2298-2301, 2016; PubMed: 27422088; DOI: 10.1016/j.xphs.2016.06.005

Experimental method

X-RAY DIFFRACTION (1.26 Å)