5B0V

Crystal Structure of Marburg virus VP40 Dimer

5B0V の概要

• エントリーDOI: 10.2210/pdb5b0v/pdb
• 分子名称: Matrix protein VP40, ETHANOL (3 entities in total)
• 機能のキーワード: marburg virus, virus assembly protein, immunosuppression, filovirus, viral protein
• 由来する生物種: Lake Victoria marburgvirus (strain Musoke-80) (MARV)
• 細胞内の位置: Virion membrane ; Peripheral membrane protein: P35260
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72080.79

構造登録者

Oda, S.,Bornholdt, Z.A.,Abelson, D.M.,Saphire, E.O. (登録日: 2015-11-05, 公開日: 2016-01-20, 最終更新日: 2016-03-09)

• 主引用文献: Oda, S.,Noda, T.,Wijesinghe, K.J.,Halfmann, P.,Bornholdt, Z.A.,Abelson, D.M.,Armbrust, T.,Stahelin, R.V.,Kawaoka, Y.,Saphire, E.O.; Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression; J.Virol., 90:1839-1848, 2015; PubMed: 26656687; DOI: 10.1128/JVI.01597-15

実験手法

X-RAY DIFFRACTION (2.81 Å)