5AXS

Crystal structure of CdCat-Fn

5AXS の概要

• エントリーDOI: 10.2210/pdb5axs/pdb
• 関連するPDBエントリー: 5CZU
• 分子名称: Ferritin light chain, N-[2-[2,5-bis(oxidanylidene)pyrrol-1-yl]ethyl]-2,3-bis(oxidanyl)benzamide, CADMIUM ION, ... (6 entities in total)
• 機能のキーワード: iron storage, metal binding protein
• 由来する生物種: Equus caballus (Horse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21083.07

構造登録者

Abe, S.,Nakajima, H.,Kondo, M.,Nakane, T.,Nakao, T.,Ueno, T.,Watanabe, Y. (登録日: 2015-08-01, 公開日: 2015-11-18, 最終更新日: 2024-10-16)

主引用文献

Nakajima, H.,Kondo, M.,Nakane, T.,Abe, S.,Nakao, T.,Watanabe, Y.,Ueno, T.
Construction of an enterobactin analogue with symmetrically arranged monomer subunits of ferritin
Chem.Commun.(Camb.), 51:16609-16612, 2015

PubMed Abstract: A set of three catecholamide ligands mimicking the structure of enterobactin was constructed on ferritin, where the 3-fold symmetric arrangement of the monomer subunits served as a foundation to form a coordination space. Similar to enterobactin, the ligands showed strong affinity for the ferric ion and formed a tris-catechoyl complex. Crystallography revealed that the complex was embedded in the entrance of the 3-fold axis channel.

PubMed: 26404005
DOI: 10.1039/c5cc06904a

実験手法

X-RAY DIFFRACTION (1.67 Å)