5AGN

Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-2-Amino-5-(2-hydroxyacetimidamido)pentanoic acid

5AGN の概要

• エントリーDOI: 10.2210/pdb5agn/pdb
• 関連するPDBエントリー: 5AGK 5AGL 5AGM 5AGO 5AGP
• 分子名称: NITRIC OXIDE SYNTHASE, BRAIN, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (7 entities in total)
• 機能のキーワード: oxidoreductase, nitric oxide synthase, inhibitor complex
• 由来する生物種: RATTUS NORVEGICUS (NORWAY RAT)
• 細胞内の位置: Cell membrane, sarcolemma ; Peripheral membrane protein : P29476
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 99902.44

構造登録者

Li, H.,Poulos, T.L. (登録日: 2015-02-02, 公開日: 2015-04-29, 最終更新日: 2024-05-08)

• 主引用文献: Tang, W.,Li, H.,Doud, E.H.,Chen, Y.,Choing, S.,Plaza, C.,Kelleher, N.L.,Poulos, T.L.,Silverman, R.B.; Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by (S)-2-Amino-5-(2-(Methylthio)Acetimidamido)Pentanoic Acid.; J.Am.Chem.Soc., 137:5980-, 2015; PubMed: 25874809; DOI: 10.1021/JACS.5B01202

実験手法

X-RAY DIFFRACTION (1.95 Å)