5C0T

Crystal structure of the mercury-bound form of MerB mutant D99S

5C0T の概要

• エントリーDOI: 10.2210/pdb5c0t/pdb
• 関連するPDBエントリー: 3F0P 5C0U 5C17 5DSF
• 分子名称: Alkylmercury lyase, MERCURY (II) ION, BROMIDE ION, ... (4 entities in total)
• 機能のキーワード: bacterial proteins, cysteine, escherichia coli, lyases, mercury, mutation, lyase, metal binding protein
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46541.60

構造登録者

Wahba, H.M.,Lecoq, L.,Stevenson, M.,Mansour, A.,Cappadocia, L.,Lafrance-Vanasse, J.,Wilkinson, K.J.,Sygusch, J.,Wilcox, D.E.,Omichinski, J.G. (登録日: 2015-06-12, 公開日: 2016-02-03, 最終更新日: 2023-09-27)

• 主引用文献: Wahba, H.M.,Lecoq, L.,Stevenson, M.,Mansour, A.,Cappadocia, L.,Lafrance-Vanasse, J.,Wilkinson, K.J.,Sygusch, J.,Wilcox, D.E.,Omichinski, J.G.; Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity.; Biochemistry, 55:1070-1081, 2016; PubMed: 26820485; DOI: 10.1021/acs.biochem.5b01298

実験手法

X-RAY DIFFRACTION (1.96 Å)