4ZWI

Surface Lysine Acetylated Human Carbonic Anhydrase II in Complex with a Sulfamate-Based Inhibitor

Summary for 4ZWI

• Entry DOI: 10.2210/pdb4zwi/pdb
• Descriptor: Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: acetylated lysines, sulfamate-based inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 30034.47

Authors

Lomelino, C.L.,Mahon, B.P.,McKenna, M. (deposition date: 2015-05-19, release date: 2015-08-26, Last modification date: 2023-11-15)

• Primary citation: Mahon, B.P.,Lomelino, C.L.,Salguero, A.L.,Driscoll, J.M.,Pinard, M.A.,McKenna, R.; Observed surface lysine acetylation of human carbonic anhydrase II expressed in Escherichia coli.; Protein Sci., 24:1800-1807, 2015; PubMed: 26266677; DOI: 10.1002/pro.2771

Experimental method

X-RAY DIFFRACTION (1.6 Å)