4ZVJ

Structure of human triose phosphate isomerase K13M

4ZVJ の概要

• エントリーDOI: 10.2210/pdb4zvj/pdb
• 分子名称: Triosephosphate isomerase, SODIUM ION, POTASSIUM ION, ... (4 entities in total)
• 機能のキーワード: triose phosphate isomerase, tim, dimer, glycolysis, isomerase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54518.15

構造登録者

Amrich, C.G.,Smith, C.,Heroux, A.,VanDemark, A.P. (登録日: 2015-05-18, 公開日: 2016-03-09, 最終更新日: 2023-09-27)

• 主引用文献: Roland, B.P.,Amrich, C.G.,Kammerer, C.J.,Stuchul, K.A.,Larsen, S.B.,Rode, S.,Aslam, A.A.,Heroux, A.,Wetzel, R.,VanDemark, A.P.,Palladino, M.J.; Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.; Biochim. Biophys. Acta, 1852:61-69, 2015; PubMed: 25463631; DOI: 10.1016/j.bbadis.2014.10.010

実験手法

X-RAY DIFFRACTION (1.6996 Å)