4ZR2

Crystal Structure of the Domain-Swapped Dimer K40L:Q108K:Y60W mutant of Human Cellular Retinol Binding Protein II

Summary for 4ZR2

Related4ZH9 4ZH6 4QZT 4QZU
DescriptorRetinol-binding protein 2, RETINAL, ACETATE ION, ... (4 entities in total)
Functional Keywordsdomain swapped dimer, domain swapping, protein folding, human cellular retinol binding protein ii, intracellular lipid binding protein, retinal, lipid binding protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm P50120
Total number of polymer chains2
Total molecular weight31790.69
Authors
Assar, Z.,Nossoni, Z.,Geiger, J.H. (deposition date: 2015-05-11, release date: 2016-06-08, Last modification date: 2017-11-01)
Primary citation
Assar, Z.,Nossoni, Z.,Wang, W.,Santos, E.M.,Kramer, K.,McCornack, C.,Vasileiou, C.,Borhan, B.,Geiger, J.H.
Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates.
Structure, 24:1590-1598, 2016
PubMed: 27524203 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2016.05.022
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8024 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21930.4%01.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution