4ZQK

Structure of the complex of human programmed death-1 (PD-1) and its ligand PD-L1.

4ZQK の概要

• エントリーDOI: 10.2210/pdb4zqk/pdb
• 分子名称: Programmed cell death 1 ligand 1, Programmed cell death protein 1, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: complex, co-stimulation, receptor-ligand complex, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein: Q9NZQ7; Membrane; Single-pass type I membrane protein: Q15116
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26385.79

構造登録者

Zak, K.M.,Dubin, G.,Holak, T.A. (登録日: 2015-05-10, 公開日: 2015-11-04, 最終更新日: 2024-01-10)

• 主引用文献: Zak, K.M.,Kitel, R.,Przetocka, S.,Golik, P.,Guzik, K.,Musielak, B.,Domling, A.,Dubin, G.,Holak, T.A.; Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.; Structure, 23:2341-2348, 2015; PubMed: 26602187; DOI: 10.1016/j.str.2015.09.010

実験手法

X-RAY DIFFRACTION (2.45 Å)