4Z7P
X-ray structure of racemic ShK Q16K toxin
Summary for 4Z7P
Entry DOI | 10.2210/pdb4z7p/pdb |
Related | 4LFS |
Descriptor | Potassium channel toxin kappa-stichotoxin-She1a, SULFATE ION (3 entities in total) |
Functional Keywords | shk toxin, toxin |
Biological source | Stoichactis helianthus (Carribean sea anemone) |
Cellular location | Secreted: P29187 |
Total number of polymer chains | 1 |
Total formula weight | 4551.26 |
Authors | Sickmier, E.A. (deposition date: 2015-04-07, release date: 2015-09-09, Last modification date: 2015-09-23) |
Primary citation | Murray, J.K.,Qian, Y.X.,Liu, B.,Elliott, R.,Aral, J.,Park, C.,Zhang, X.,Stenkilsson, M.,Salyers, K.,Rose, M.,Li, H.,Yu, S.,Andrews, K.L.,Colombero, A.,Werner, J.,Gaida, K.,Sickmier, E.A.,Miu, P.,Itano, A.,McGivern, J.,Gegg, C.V.,Sullivan, J.K.,Miranda, L.P. Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3. J.Med.Chem., 58:6784-6802, 2015 Cited by PubMed: 26288216DOI: 10.1021/acs.jmedchem.5b00495 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
Download full validation report