4Z02

Crystal structure of BRD1 in complex with Isoquinoline-3-carboxylic acid

Summary for 4Z02

• Entry DOI: 10.2210/pdb4z02/pdb
• Descriptor: Bromodomain-containing protein 1, isoquinoline-3-carboxylic acid, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: brpf2 fragment, brd1, structural genomics, structural genomics consortium, sgc, histone-binding protein
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : O95696
• Total number of polymer chains: 2
• Total formula weight: 28911.97

Authors

DONG, A.,IQBAL, A.,WALKER, J.R.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,BROWN, P.J.,Structural Genomics Consortium (SGC) (deposition date: 2015-03-25, release date: 2015-04-22, Last modification date: 2023-09-27)

• Primary citation: IQBAL, A.,DONG, A.,WALKER, J.R.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,BROWN, P.J.,Structural Genomics Consortium (SGC); Crystal structure of BRD1 incomplex with Isoquinoline-3-carboxylic acid; to be published,

Experimental method

X-RAY DIFFRACTION (1.87 Å)