4YZ4
Crystal Structure of Streptococcus pneumoniae NanC, in complex with N-Acetylneuraminic acid.
Summary for 4YZ4
| Entry DOI | 10.2210/pdb4yz4/pdb |
| Descriptor | Sialidase, NanC, N-acetyl-alpha-neuraminic acid, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | sialidase, neuraminidase, beta-propeller, cbm40, hydrolase |
| Biological source | Streptococcus pneumoniae |
| Total number of polymer chains | 2 |
| Total formula weight | 153764.98 |
| Authors | Lukacik, P.,Owen, C.D.,Potter, J.A.,Taylor, G.L.,Walsh, M.A. (deposition date: 2015-03-24, release date: 2015-09-23, Last modification date: 2020-07-29) |
| Primary citation | Owen, C.D.,Lukacik, P.,Potter, J.A.,Sleator, O.,Taylor, G.L.,Walsh, M.A. Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290:27736-27748, 2015 Cited by PubMed: 26370075DOI: 10.1074/jbc.M115.673632 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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