4YN6

Structural Insight reveals dynamics in repeating r(CAG) transcript found in Huntington's disease (HD) and Spinocerebellar ataxias (SCAs)

Summary for 4YN6

• Entry DOI: 10.2210/pdb4yn6/pdb
• Descriptor: RNA (5'-R(P*UP*UP*GP*GP*GP*CP*CP*AP*GP*CP*AP*GP*CP*AP*GP*GP*UP*CP*C)-3'), PHOSPHATE ION (3 entities in total)
• Functional Keywords: rna, trinucleotide repeat, huntington's disease (hd), spinocerebellar ataxias (scas)
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 12407.32

Authors

Tawani, A.,Kumar, A. (deposition date: 2015-03-09, release date: 2015-04-22, Last modification date: 2024-03-20)

• Primary citation: Tawani, A.,Kumar, A.; Structural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs); Plos One, 10:e0131788-e0131788, 2015; PubMed: 26148061; DOI: 10.1371/journal.pone.0131788

Experimental method

X-RAY DIFFRACTION (2.301 Å)