4YM0

Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with lacto-N-tetraose (LNT)

4YM0 の概要

• エントリーDOI: 10.2210/pdb4ym0/pdb
• 関連するPDBエントリー: 4YLZ 4YM1 4YM2 4YM3
• 関連するBIRD辞書のPRD_ID: PRD_900004
• 分子名称: Galectin-4, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: galectin, lectin, carbohydrate binding protein, lacto-n-tetraose, carbohydrate recognition, beta sandwich, sugar binding protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 70082.16

構造登録者

Bum-Erdene, K.,Blanchard, H. (登録日: 2015-03-06, 公開日: 2015-07-01, 最終更新日: 2024-02-28)

• 主引用文献: Bum-Erdene, K.,Leffler, H.,Nilsson, U.J.,Blanchard, H.; Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens.; Febs J., 282:3348-3367, 2015; PubMed: 26077389; DOI: 10.1111/febs.13348

実験手法

X-RAY DIFFRACTION (2.3 Å)