Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y:A32Y:F3Q mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.58 angstrom resolution

Summary for 4YKO

Related4YFP 4YFR 4YFQ 4I9S 2G7B 4RUU 4EEJ
DescriptorCellular retinoic acid-binding protein 2, RETINAL (3 entities in total)
Functional Keywordsrhodopsin mimic, photoswitchable protein, retinal isomerization, retinal psb, protein engineering, retinal iminium pka change by isomerization, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm P29373
Total number of polymer chains2
Total molecular weight31802.47
Nosrati, M.,Geiger, J. (deposition date: 2015-03-04, release date: 2016-03-09, Last modification date: 2016-08-03)
Primary citation
Nosrati, M.,Berbasova, T.,Vasileiou, C.,Borhan, B.,Geiger, J.H.
A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution.
J.Am.Chem.Soc., 138:8802-8808, 2016
PubMed: 27310917 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.6b03681
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.221302.0%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution