4YKM

Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y:A32W:F3Q mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.58 angstrom resolution

Summary for 4YKM

Related4YFP 4YFQ 4YBP 4I9S 4RUU 2G7B
DescriptorCellular retinoic acid-binding protein 2, RETINAL (3 entities in total)
Functional Keywordsphotoswitchable protein, rhodopsin mimic, retinal isomerization, retinal iminium pka change, protein engineering, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm P29373
Total number of polymer chains2
Total molecular weight31848.54
Authors
Nosrati, M.,Geiger, J.H. (deposition date: 2015-03-04, release date: 2016-03-09, Last modification date: 2016-08-03)
Primary citation
Nosrati, M.,Berbasova, T.,Vasileiou, C.,Borhan, B.,Geiger, J.H.
A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution.
J.Am.Chem.Soc., 138:8802-8808, 2016
PubMed: 27310917 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.6b03681
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.58 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.211401.6%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report