4YCM

Crystal structure of the calcium pump with bound marine macrolide BLS

Summary for 4YCM

Entry DOI	10.2210/pdb4ycm/pdb
Related	4YCN
Descriptor	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SODIUM ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	membrane protein, p-type atpase, had fold, ca2+, ion pump, hydrolase
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	1
Total formula weight	111932.58
Authors	Morita, M.,Ogawa, H.,Ohno, O.,Yamori, T.,Suenaga, K.,Toyoshima, C. (deposition date: 2015-02-20, release date: 2016-01-13, Last modification date: 2020-02-05)
Primary citation	Morita, M.,Ogawa, H.,Ohno, O.,Yamori, T.,Suenaga, K.,Toyoshima, C. Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding Febs Lett., 589:1406-1411, 2015 Cited by PubMed: 25957767 DOI: 10.1016/j.febslet.2015.04.056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation