Reduced CYPOR with 2'-AMP

Summary for 4YAL

Related4Y9R 4Y9U 4YAF 4YAO 4YAU 4YAW
DescriptorNADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... (6 entities in total)
Functional Keywordscytochrome p450 reductase, fmn binding, semiquinone, oxidoreductase
Biological sourceRattus norvegicus (Rat)
Cellular locationEndoplasmic reticulum membrane ; Single-pass membrane protein ; Cytoplasmic side  P00388
Total number of polymer chains2
Total molecular weight144918.99
Xia, C.,Kim, J.J.P. (deposition date: 2015-02-17, release date: 2016-03-02, Last modification date: 2017-09-20)
Primary citation
Rwere, F.,Xia, C.,Im, S.,Haque, M.M.,Stuehr, D.J.,Waskell, L.,Kim, J.J.
Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291:14639-14661, 2016
PubMed: 27189945 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M116.724625
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.227701.1%5.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report