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4Y4F

Crystal structure of the mCD1d/GCK127/iNKTCR ternary complex

Summary for 4Y4F
Entry DOI10.2210/pdb4y4f/pdb
Related4Y16 4Y2D 4Y4H 4Y4K
DescriptorAntigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, Chimeric TCR Valpha14/Jalpha18 chain (mouse variable domain/ human constant domain), ... (7 entities in total)
Functional Keywordsmhc-fold, ig-fold, glycolipid antigen presentation, t cell receptor, immune system
Biological sourceMus musculus (Mouse)
More
Total number of polymer chains8
Total formula weight191835.32
Authors
Zajonc, D.M.,Yu, E.D. (deposition date: 2015-02-10, release date: 2015-05-27, Last modification date: 2023-09-27)
Primary citationBirkholz, A.,Nemcovic, M.,Yu, E.D.,Girardi, E.,Wang, J.,Khurana, A.,Pauwels, N.,Franck, R.W.,Tsuji, M.,Howell, A.,Calenbergh, S.,Kronenberg, M.,Zajonc, D.M.
Structural modifications of alphaGalCer in both lipid and carbohydrate moiety influence activation of murine and human iNKT cells
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.19 Å)
Structure validation

217705

數據於2024-03-27公開中

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