4Y0I
GABA-aminotransferase inactivated by conformationally-restricted inactivator
Summary for 4Y0I
Entry DOI | 10.2210/pdb4y0i/pdb |
Descriptor | 4-aminobutyrate aminotransferase, mitochondrial, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... (5 entities in total) |
Functional Keywords | synthesis, biological evaluation, mechanistic studies of con-formationally-restricted gaba-aminotransferase inactivators, transferase |
Biological source | Sus scrofa (Pig) |
Total number of polymer chains | 4 |
Total formula weight | 210995.93 |
Authors | Wu, R.,Sanishvili, R.,Lee, H.V.,Dustin, D.H.,Emma, D.,Neil, K.,Silverman, R.B.,Liu, D. (deposition date: 2015-02-06, release date: 2016-02-17, Last modification date: 2024-02-28) |
Primary citation | Lee, H.V.,Dustin, D.H.,Wu, R.,Emma, D.,Sanishvili, R.,Liu, D.,Neil, K.,Silverman, R.B. GABA-aminotransferase inactivated by conformationally-restricted inactivator To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.662 Å) |
Structure validation
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