4Y0I

GABA-aminotransferase inactivated by conformationally-restricted inactivator

Summary for 4Y0I

• Entry DOI: 10.2210/pdb4y0i/pdb
• Descriptor: 4-aminobutyrate aminotransferase, mitochondrial, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... (5 entities in total)
• Functional Keywords: synthesis, biological evaluation, mechanistic studies of con-formationally-restricted gaba-aminotransferase inactivators, transferase
• Biological source: Sus scrofa (Pig)
• Total number of polymer chains: 4
• Total formula weight: 210995.93

Authors

Wu, R.,Sanishvili, R.,Lee, H.V.,Dustin, D.H.,Emma, D.,Neil, K.,Silverman, R.B.,Liu, D. (deposition date: 2015-02-06, release date: 2016-02-17, Last modification date: 2024-02-28)

• Primary citation: Lee, H.V.,Dustin, D.H.,Wu, R.,Emma, D.,Sanishvili, R.,Liu, D.,Neil, K.,Silverman, R.B.; GABA-aminotransferase inactivated by conformationally-restricted inactivator; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.662 Å)