4XS9

Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis

Summary for 4XS9

• Entry DOI: 10.2210/pdb4xs9/pdb
• Related: 4XQP 4XS7 4XSA 4XSB
• Descriptor: Daunorubicin-doxorubicin polyketide synthase, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-[2-(propanoylamino)ethyl]-beta-alaninamide (3 entities in total)
• Functional Keywords: polyketide, daunorubicin, natural product, starter unit, transferase
• Biological source: Streptomyces peucetius
• Total number of polymer chains: 2
• Total formula weight: 79655.67

Authors

Jackson, D.R.,Valentic, T.R.,Tsai, S.C.,Patel, A.,Mohammed, L.,Vasilakis, K.,Wattana-amorn, P.,Long, P.F.,Crump, M.P.,Crosby, J. (deposition date: 2015-01-22, release date: 2016-01-27, Last modification date: 2023-09-27)

• Primary citation: Jackson, D.R.,Valentic, T.R.,Tsai, S.C.,Patel, A.,Mohammed, L.,Vasilakis, K.,Wattana-amorn, P.,Long, P.F.,Crump, M.P.,Crosby, J.; Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.002 Å)