4XRO

Disulfide stabilized HIV-1 CA hexamer 4mut (S41A, Q67H, V165I, L172I)

4XRO の概要

• エントリーDOI: 10.2210/pdb4xro/pdb
• 分子名称: Capsid protein p24 (2 entities in total)
• 機能のキーワード: viral protein, capsid
• 由来する生物種: Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)
• 細胞内の位置: Gag polyprotein: Host cell membrane; Lipid- anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P12493
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25469.32

構造登録者

Price, A.J.,James, L.C. (登録日: 2015-01-21, 公開日: 2015-07-15, 最終更新日: 2024-01-10)

• 主引用文献: Zhou, J.,Price, A.J.,Halambage, U.D.,James, L.C.,Aiken, C.; HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry.; J.Virol., 89:9068-9079, 2015; PubMed: 26109731; DOI: 10.1128/JVI.00340-15

実験手法

X-RAY DIFFRACTION (2.01 Å)