4XO2

crystal structure of GnsA from E.coli

4XO2 の概要

• エントリーDOI: 10.2210/pdb4xo2/pdb
• 関連するPDBエントリー: 4XO1
• 分子名称: Protein GnsA (2 entities in total)
• 機能のキーワード: suppressor, protein binding
• 由来する生物種: Escherichia coli (strain K12)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 13932.07

構造登録者

Zhan, L.H.,Gao, Z.Q.,Wei, Y.,Dong, Y.H. (登録日: 2015-01-16, 公開日: 2015-06-17, 最終更新日: 2024-03-20)

主引用文献

Wei, Y.,Zhan, L.,Gao, Z.,Prive, G.G.,Dong, Y.
Crystal structure of GnsA from Escherichia coli
Biochem.Biophys.Res.Commun., 462:1-7, 2015

PubMed Abstract: Escherichia Coli GnsA is a regulator of phosphatidylethanolamine synthesis and functions as a suppressor of both a secG null mutation and fabA6 mutations. GnsA may also be a toxin with the cognate antitoxin YmcE. Here we report the crystal structure of GnsA to 1.8 Å. GnsA forms a V shaped hairpin structure that is tightly associated into a homodimer. Our comprehensive structural study suggests that GnsA is structurally similar to an outer membrane protein, suggesting a function of protein binding.

PubMed: 25839658
DOI: 10.1016/j.bbrc.2015.03.133

実験手法

X-RAY DIFFRACTION (1.952 Å)