4XFR

Crystal structure of a domain of unknown function (DUF1537) from Bordetella bronchiseptica (BB3215), Target EFI-511620, with bound citrate, domain swapped dimer, space group P6522

Summary for 4XFR

• Entry DOI: 10.2210/pdb4xfr/pdb
• Descriptor: Uncharacterized protein, CITRIC ACID (3 entities in total)
• Functional Keywords: enzyme function initiative, efi, structural genomics, unknown function
• Biological source: Bordetella bronchiseptica
• Total number of polymer chains: 2
• Total formula weight: 88181.87

Authors

Vetting, M.W.,Al Obaidi, N.F.,Toro, R.,Morisco, L.L.,Benach, J.,Wasserman, S.R.,Attonito, J.D.,Scott Glenn, A.,Chamala, S.,Chowdhury, S.,Lafleur, J.,Love, J.,Seidel, R.D.,Whalen, K.L.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2014-12-28, release date: 2015-01-28, Last modification date: 2017-11-22)

• Primary citation: Zhang, X.,Carter, M.S.,Vetting, M.W.,San Francisco, B.,Zhao, S.,Al-Obaidi, N.F.,Solbiati, J.O.,Thiaville, J.J.,de Crecy-Lagard, V.,Jacobson, M.P.,Almo, S.C.,Gerlt, J.A.; Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.; Proc.Natl.Acad.Sci.USA, 113:E4161-E4169, 2016; PubMed: 27402745; DOI: 10.1073/pnas.1605546113

Experimental method

X-RAY DIFFRACTION (2 Å)