4XFI

cysteine dioxygenase variant - Y157F at pH 6.2 with homocysteine

4XFI の概要

• エントリーDOI: 10.2210/pdb4xfi/pdb
• 関連するPDBエントリー: 4EXT 4IEO 4IEP 4IEQ 4IER 4IES 4IET 4IEU 4IEV 4IEW 4IEX 4IEY 4IEZ 4JTN 4JTO 4KWK 4KWL 4PIX 4PIY 4PIZ 4PJY 4XEZ 4XF0 4XF1 4XF3 4XF4 4XF9 4XFA 4XFB 4XFC 4XFF 4XFG 4XFH
• 分子名称: Cysteine dioxygenase type 1, FE (III) ION, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, ... (4 entities in total)
• 機能のキーワード: cupin fold, cysteine to cysteine sulfinic acid catalysis, thiol dioxygenase, oxidoreductase
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23233.92

構造登録者

Driggers, C.M.,Karplus, P.A. (登録日: 2014-12-26, 公開日: 2016-02-24, 最終更新日: 2024-04-03)

• 主引用文献: Driggers, C.M.,Kean, K.M.,Hirschberger, L.L.,Cooley, R.B.,Stipanuk, M.H.,Karplus, P.A.; Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase.; J. Mol. Biol., 428:3999-4012, 2016; PubMed: 27477048; DOI: 10.1016/j.jmb.2016.07.012

実験手法

X-RAY DIFFRACTION (1.4 Å)