4XET

Fe-Cl bound Y157F CDO at pH ~7.0 in the presence of azide

Summary for 4XET

• Entry DOI: 10.2210/pdb4xet/pdb
• Related: 4IEO 4IEP 4IEQ 4IER 4IES 4IET 4IEU 4IEV 4IEW 4IEX 4IEY 4IEZ
• Descriptor: Cysteine dioxygenase type 1, FE (III) ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: cupin fold, cysteine to cysteine sulfinic acid catalysis, cytosol, thiol dioxygenase, oxidoreductase
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 1
• Total formula weight: 23134.19

Authors

Driggers, C.M.,Karplus, P.A. (deposition date: 2014-12-24, release date: 2016-04-06, Last modification date: 2023-09-27)

• Primary citation: Driggers, C.M.,Kean, K.M.,Hirschberger, L.L.,Cooley, R.B.,Stipanuk, M.H.,Karplus, P.A.; Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase.; J. Mol. Biol., 428:3999-4012, 2016; PubMed: 27477048; DOI: 10.1016/j.jmb.2016.07.012

Experimental method

X-RAY DIFFRACTION (1.3 Å)