4XE1
Human carbonic anhydrase II in complex with 6-SULFAMOYL-SACCHARIN
Summary for 4XE1
Entry DOI | 10.2210/pdb4xe1/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | cytoplasm, lyase, inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 30327.88 |
Authors | Alterio, V.,De Simone, G. (deposition date: 2014-12-21, release date: 2015-03-18, Last modification date: 2024-01-10) |
Primary citation | Alterio, V.,Tanc, M.,Ivanova, J.,Zalubovskis, R.,Vozny, I.,Monti, S.M.,Di Fiore, A.,De Simone, G.,Supuran, C.T. X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor. Org.Biomol.Chem., 13:4064-4069, 2015 Cited by PubMed: 25733161DOI: 10.1039/c4ob02648a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report