4XDG

Crystal Structure of Quinone Reductase II in complex with 2-(4-aminophenyl)-5-methoxy-1-oxy-indol-3-one molecule

4XDG の概要

• エントリーDOI: 10.2210/pdb4xdg/pdb
• 分子名称: Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (6 entities in total)
• 機能のキーワード: qr2, fad, flavoprotein, metal-binding, oxidoreductase, indolone oxide
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm: P16083
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54487.71

構造登録者

Sirigu, S.,Nepveu, F.,Vuillard, L.,Ferry, G.,Isabet, T.,Thompson, A.,Boutin, J.A. (登録日: 2014-12-19, 公開日: 2016-01-13, 最終更新日: 2024-05-08)

• 主引用文献: Cassagnes, L.E.,Rakotoarivelo, N.,Sirigu, S.,Perio, P.,Najahi, E.,Chavas, L.M.,Thompson, A.,Gayon, R.,Ferry, G.,Boutin, J.A.,Valentin, A.,Reybier, K.,Nepveu, F.; Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives.; Molecules, 22:-, 2017; PubMed: 28146103; DOI: 10.3390/molecules22020210

実験手法

X-RAY DIFFRACTION (1.5 Å)