4X9Z

Dimeric conotoxin alphaD-GeXXA

Summary for 4X9Z

• Entry DOI: 10.2210/pdb4x9z/pdb
• Descriptor: alphaD-conotoxin GeXXA from the venom of Conus generalis (2 entities in total)
• Functional Keywords: alpha-conotoxin, gexxa, nicotinic acetylcholine receptor, homodimer, toxin
• Biological source: Conus generalis
• Total number of polymer chains: 2
• Total formula weight: 11289.45

Authors

Xu, S.,Zhang, T.,Kompella, S.,Adams, D.,Ding, J.,Wang, C. (deposition date: 2014-12-12, release date: 2015-12-02, Last modification date: 2020-02-05)

• Primary citation: Xu, S.,Zhang, T.,Kompella, S.N.,Yan, M.,Lu, A.,Wang, Y.,Shao, X.,Chi, C.,Adams, D.J.,Ding, J.,Wang, C.; Conotoxin alpha D-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors; Sci Rep, 5:14261-14261, 2015; PubMed: 26395518; DOI: 10.1038/srep14261

Experimental method

X-RAY DIFFRACTION (1.5 Å)